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AQA Biology 4.3.1.1 · 4.3.1.6

Communicable diseases and defences

Pathogens spread from host to host. Follow one in, switch off a defence, and see what stops it next.

Start here

Germs everywhere.

Germs are on door handles, phones and your own hands. You touch thousands of them every day.

If you had to guess, would a germ get into your body more easily through unbroken skin, or through a cut?

Pathogens · how they spread

Four kinds of pathogen, a few ways in.

Pathogens are microorganisms that cause infectious disease: viruses, bacteria, protists and fungi. They may infect plants or animals. Bacteria and viruses reproduce rapidly inside the body. Bacteria may produce toxins that damage tissues; viruses live and reproduce inside cells, causing cell damage.

Pick a route of spread, then see what breaks it.

Pick a route.

Vaccination stops many diseases spreading at all: in Vaccination. The named diseases are in Viral, Bacterial and Fungal and protist diseases.

Non-specific defences

Keep them out.

Most pathogens are stopped before they get into the body. Pick how a pathogen arrives, then switch that defence off and see how far it gets.

The nose traps particles that may contain pathogens. In the trachea and bronchi, mucus traps pathogens and cilia move the mucus up to the throat, where it is swallowed.

The immune system · white blood cells

If a pathogen gets in.

If a pathogen enters the body, the immune system tries to destroy it. White blood cells do this in three ways. Pick each one.

Phagocytes engulf pathogens and digest them. They attack any pathogen they meet.

Some white blood cells stay in the blood as memory cells, so if the same pathogen comes back the right antibodies are made quickly: more in Vaccination.

Think again · who makes antibodies?

“Phagocytes make antibodies.”

Your call

Choose

Which white blood cells make antibodies?

Sort

Barrier or white blood cell?

Place each defence.

Tap a card, then tap the box it belongs in. Tap a placed card to take it back.

Command words in this lesson

Describe
Each defence, and what it does to the pathogen.
Explain
How a defence stops the pathogen, link by link.
Give
One way to break a route of spread.

Key fact

Barriers keep most pathogens out. White blood cells destroy those that get in: phagocytosis, antibodies and antitoxins.

Key note · AQA 4.3.1.1, 4.3.1.6

Communicable diseases and defences

  1. Pathogens are microorganisms that cause infectious disease: viruses, bacteria, protists and fungi. They infect plants or animals.
  2. They spread by air, water, direct contact, or a vector. Break the route: isolate, treat water, hygiene and condoms, control vectors.
  3. Barriers: skin; the nose; mucus and cilia in the trachea and bronchi; acid in the stomach.
  4. White blood cells: phagocytosis; antibody production; antitoxin production.

Photograph this card. Tomorrow, cover it and say each line first.

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