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AQA Biology 4.1.2.3

Stem cells

Three sources, one difference that matters: how many kinds of cell each can become. Compare them, then weigh up using them.

Start here

A cutting on the windowsill.

A short piece snipped from a houseplant is stood in a glass of water. A few weeks later it has roots, and soon it is a whole new plant.

If you had to guess, could a piece of your arm grow into a whole new you?

What can it become?

Three kinds of stem cell.

A stem cell is an undifferentiated cell. It can divide to make many more cells of the same type, and other kinds of cell can arise from it by differentiation. Pick a source and see which cells it can become.

Can become

Most types of human cell. They come from an early embryo, about 5 days old.

Used for

May be able to help conditions such as diabetes and paralysis, by making the cells that are missing or damaged.

Therapeutic cloning

An embryo with the patient’s own genes.

In therapeutic cloning, an embryo is produced with the same genes as the patient. Stem cells from the embryo are not rejected by the patient’s body, so they may be used for medical treatment. Treatment with stem cells may be able to help conditions such as diabetes and paralysis. Tap each side.

Think again · a copy of the patient?

“Therapeutic cloning makes a baby copy of the patient.”

Your call

Choose

What is therapeutic cloning used to produce?

Sort

Embryonic, bone marrow or meristem?

Place each statement.

Tap a card, then tap the box it belongs in. Tap a placed card to take it back.

Command words in this lesson

Describe
Where the stem cells come from, and what they can become.
Compare
Embryonic against adult: the range of cells.
Evaluate
Benefits, practical risks and objections, then a judgement.

Key fact

Embryonic stem cells can become most types of human cell. Adult bone marrow stem cells form a limited range, including blood cells. Meristem cells can become any type of plant cell, throughout the plant’s life.

Key note · AQA 4.1.2.3

Stem cells

  1. A stem cell is an undifferentiated cell that can divide to make more cells, and can differentiate into other types of cell.
  2. Embryonic stem cells can become most types of human cell. They may help conditions such as diabetes and paralysis.
  3. Adult bone marrow stem cells form a limited range of cells, including blood cells.
  4. Therapeutic cloning: an embryo with the patient’s genes, so its stem cells are not rejected.
  5. Risks include transfer of viral infection; some people have ethical or religious objections.
  6. Meristems, at root and shoot tips, can become any plant cell throughout the plant’s life: used to clone rare species and crops.

Photograph this card. Tomorrow, cover it and say each line first.

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